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Tolerance Tolerance to alprazolam may well establish from ongoing therapy. Tolerance is usually a physiological point out characterised by a minimized reaction to your drug after repeated administration (i.e., the next dose of a drug is required to produce exactly the same outcome that was as soon as obtained in a lower dose).

Alprazolam is a secure and efficient medication when made use of as directed. Benzodiazepines may well make psychological and/or Actual physical dependence (addiction) even though utilized as encouraged.

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In a managed postmarketing discontinuation analyze of worry dysfunction people which in comparison the suggested taper routine having a slower taper routine, no distinction was noticed involving the groups within the proportion of patients who tapered to zero dose; having said that, the slower agenda was connected to a reduction in symptoms affiliated with a withdrawal syndrome.

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